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生物化学 美国医师执照考试 第3版2025|PDF|Epub|mobi|kindle电子书版本百度云盘下载

生物化学 美国医师执照考试 第3版
  • 威儿科克斯著 著
  • 出版社： 北京医科大学出版社
  • ISBN：7565904820
  • 出版时间：2013
  • 标注页数：109页
  • 文件大小：38MB
  • 文件页数：120页
  • 主题词：

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图书目录

1 Acid—Base Relationships1

Ⅰ．Acidic dissociation1

Ⅱ．Measures of acidity1

Ⅲ．Buffers2

Ⅳ．Acid-base balance3

Ⅴ．Acid-base disorders3

Ⅵ．Clinical relevance:diabetic ketoacidosis4

2 Amino Acids and Proteins5

Ⅰ．Functions of proteins5

Ⅱ．Proteins as polypeptides5

Ⅲ．Protein structure6

Ⅳ．Protein solubility and R-groups9

Ⅴ．Protein denaturation9

Ⅵ．Clinical relevance9

3 Enzymes11

Ⅰ．Energy relationships11

Ⅱ．Free-energy change11

Ⅲ．Enzymes as biological catalysts12

Ⅳ．Michaelis-Menten equation13

Ⅴ．Lineweaver-Burk equation14

Ⅵ．Enzyme regulation15

Ⅶ．Clinical relevance:methanol and ethylene glycol poisoning18

4 Citric Acid Cycle and Oxidative Phosphorylation19

Ⅰ．Cellular energy and adenosine triphosphate19

Ⅱ．Citric acid cycle19

Ⅲ．Products of the citric acid cycle(one revolution)20

Ⅳ．Synthetic function of the citric acid cycle20

Ⅴ．Regulation of the citric acid cycle21

Ⅵ．Electron transport and oxidative phosphorylation21

Ⅶ．Chemiosmotic hypothesis21

Ⅷ．Clinical relevance23

5 Carbohydrate Metabolism24

Ⅰ．Carbohydrate digestion and absorption24

Ⅱ．Glycogen metabolism24

Ⅲ．Glycolysis25

Ⅳ．Gluconeogenesis27

Ⅴ．Regulation of glycolysis and gluconeogenesis29

Ⅵ．Pentose phosphate pathway29

Ⅶ．Sucrose and lactose metabolism31

Ⅷ．Clinical relevance31

6 Lipid Metabolism33

Ⅰ．Lipid function33

Ⅱ．Lipid digestion33

Ⅲ．Lipoprotein transport and metabolism34

Ⅳ．Oxidation of fatty acids36

Ⅴ．Fatty acid synthesis37

Ⅵ．Glycerolipid synthesis40

Ⅶ．Sphingolipid synthesis42

Ⅷ．Cholesterol synthesis42

Ⅸ．Clinical relevance43

7 Amino Acid Metabolism45

Ⅰ．Functions of amino acids45

Ⅱ．Removal of amino acid nitrogen45

Ⅲ．Urea cycle and detoxification of NH？45

Ⅳ．Carbon skeletons of amino acids47

Ⅴ．Clinical relevance:inherited(inborn)errors of amino acid metabolism49

8 Nucleotide Metabolism52

Ⅰ．Nucleotide structure52

Ⅱ．Nucleotide function52

Ⅲ．Purine nucleotide synthesis52

Ⅳ．Pyrimidine nucleotide synthesis55

Ⅴ．Deoxyribonucleotide synthesis56

Ⅵ．Nucleotide degradation59

Ⅶ．Clinical relevance60

9 Nutrition62

Ⅰ．Energy needs62

Ⅱ．Macronutrients62

Ⅲ．Micronutrients:the fat-soluble vitamins65

Ⅳ．Micronutrients:the water-soluble vitamins68

Ⅴ．Minerals71

10 Gene Expression74

Ⅰ．Genetic information74

Ⅱ．DNA and RNA:nucleic acid structure74

Ⅲ．DNA synthesis(replication)76

Ⅳ．Transcription79

Ⅴ．Translation(protein synthesis)82

Ⅵ．Mutations85

11 Biochemical Technology87

Ⅰ．Protein purification87

Ⅱ．Protein analysis87

Ⅲ．DNA analysis88

Ⅳ．Cloning of recombinant DNA and protein91

Ⅴ．Clinical relevance94

12 Hormones95

Ⅰ．Overview95

Ⅱ．Classification of hormones95

Ⅲ．Mechanisms of hormone action96

Ⅳ．Hormones that regulate fuel metabolism97

Ⅴ．Hormones that regulate salt and water balance98

Ⅵ．Hormones that regulate calcium and phosphate metabolism99

Ⅶ．Hormones that regulate body size and metabolism99

Ⅷ．Hormones that regulate the male reproductive system100

Ⅸ．Hormones that regulate the female reproductive system100

Ⅹ．Clinical relevance: diabetes mellitus101

Index102

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